Mauricio Pochettino's side now lie third in Group E after collecting only four points from as many matches, and anything less than a victory at the Stade Louis II - coupled with Bayer Leverkusen beating CSKA Moscow - would render them unable to qualify for the last 16.
Tottenham sit third in Group E, two points behind Bayer Leverkusen, and realistically must win in France to keep their qualification hopes alive.
"The first is a game we must win against Monaco and it's for that reason we need to have the mentality and feeling that we can go to Monaco and win".
Tottenham's bid to progress from the group stages of Europe's premier competition hangs in the balance. "It's impossible to win a game after five minutes, we need to play 90 minutes, be clever". Beating Monaco at home is a huge ask though as the French side have not lost there this season.
"The feeling after the Chelsea game last season is one that I never want to feel again", said the England full-back.
Tottenham travels to the Mediterranean principality boosted by claiming a first win in eight matches at the weekend, when it beat West Ham United 3-2 after a dramatic late fightback in the Premier League.
Spurs go into the match on the back of a 3-2 win over West Ham on Saturday.
Going out of the Champions League won't change that they have a young, talented team with an exciting academy and a new stadium opening soon that will completely change the club's finances.
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Goalie Marc-Andre Fleury allowed four goals on 35 shots, but was victimized a few times by sloppy play in the defensive zone. Tierney scored a short-handed goal two minutes into the contest after he stole a pass and raced unguarded to beat Kinkaid.
'We have worked so hard for years and years to get this opportunity and we know if we don't win then we are more or less out of the competition. "We need to congratulate the people in the academy because the work they are doing is fantastic from a long time ago".
That 2-2 draw in May confirmed Leicester City as Premier League champions as Chelsea came from two goals down to deny their London rivals the win they needed to stay in the race.
"Our selection for tomorrow will be if the players that are fit or not, that can play 90 minutes or not".
'We have to think, game by game, and now we have Tottenham at home.
"I am happy at the club and want to be here for a long, long time", Kane, whose current contract runs till June 2020, told British media.
"The only thing we can do now is try to recover the situation by winning in Monaco".
They have no injury worries, but the biggest concern for both teams could be the weather, with the rain in the region on Monday forecast to continue well into Tuesday.