If City's front three of Aguero, Leroy Sane and Raheem Sterling play as well as they did in the first leg, City will claim the goals that Guardiola desires.
Guardiola will want his back-line to be more disciplined than they were at Etihad Stadium but, in the space of three weeks, he can not mould them into a solid unit that will be able to keep Monaco out.
Falcao, who endured a nightmare time at Manchester United and Chelsea, has 22 goals in 22 starts this season and four goals in five European games.
The fifth came eight minutes from the end when Silva fed the ball through to Aguero and he slid the ball across for Sane to tap home.
Falcao then picked up a punt forward, powered past Stones easily and then produced a lovely chip over Caballero to make up for his spot-kick blunder in superb fashion.
"All of Europe will watch us, to analyse us, to kill us if we don't win or say how good we are if we do", added the Spaniard.
With just two goals to his name since the end of November, recent events have fuelled the speculation that Aguero, 28, could end his six-year stay with City once the current campaign is over.
"We are going to fly to Monaco to score as many goals as possible", he said.
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Other Monaco players were more open about the crushing blow.
A storming Mbappe break moments later was ultimately stopped by City's centre-back pairing of Stones and Nicolas Otamendi, before Djibril Sidibe saw his 11th minute shot blocked en route to goal. Guardiola said there should be no doubts about the threat they pose.
Guardiola confirmed City captain Vincent Kompany's injury problems are still continuing after he missed the Huddersfield game and he will sit out the first leg against Monaco.
"I would like to see how many teams are able to get a clean sheet against Monaco this season". Beside this, there is the big offensive role played by the full backs (Sidibe and Mendy) who use the wings. "We don't want it, we don't need it", he said.
Caballero, who dived to his left to save Falcao's weak spot-kick, said: "Unbelievable".
"The system, the way Monaco play now is flawless for him".
Aguero twice equalised, with a 58th-minute strike that burst past Danijel Subasic in the Monaco goal and a sweetly-struck volley 13 minutes later. Jardim's team has momentum, confidence, skill, power and balance. When they were courageous on Tuesday night, they were risky, and that is what they have to do in Monaco too. Even in Barcelona and Bayern Munich I thought I am lucky to be here.