Meanwhile, Fillon, head of the Republican party, who lost ground earlier on in the campaign after being implicated in a scandal allegedly arranging fictitious jobs for his wife, walked away with 19.9% of the votes. This result is historic.
But even without having progressed to the final round, Dupont-Aignan still wields power.
National Front vice president Steeve Brios said: "The voters who voted for Mr Melenchon are angry voters". His campaign are calling him the "king-maker", which may be pushing the truth somewhat.
ANALYST TAKE: "In Macron, we see the strongest opponent pitted against Le Pen, in what is likely to be the final vote of confidence for the European Union in what was always going to be a critical year for the future of Europe", said Joshua Mahony, market analyst at IG.
During her visit to Moscow in late March when she met Vladimir Putin, Le Pen pointed out that she is "in favor of developing relations with Russia" and called for cooperation with Moscow in the fight against terrorism.
With 99 percent of ballots counted, Macron has 23.82 percent of the vote and Le Pen 21.57 percent.
Browns have zeroed in on choice with No. 1 draft pick
It doesn't mean that if there's a player there we might not go take a shot. " This is an important draft for us ". Brown said the team has narrowed its focus on a few players to consider taking first.
Le Pen, who has been hoping to emulate Donald Trump's victory in the United States, said the French faced a choice between "runaway globalisation" and a protectionist France.
Le Pen's National Front (FN) will seek to highlight the centrist's past as a millionaire investment banker, advisor to unpopular President Francois Hollande and pro-globalisation economy minister in the weeks ahead.
The Interior Ministry announced that the turnout had reached 69.4 percent three hours before the polls closed, compared with 70.6 percent in the first round of presidential voting in 2012.
"Macron made a speech as if he'd already won", Le Pen's top aide Florian Philippot said Monday, before attacking Macron for copying the style of former right-wing leader Nicolas Sarkozy. He said that they express a choice "outside the system". And, just as in post-Brexit Britain, her hostility to the European Union could jeopardise research funding. "To many, it was clear that Fillon would never touch the pensions of French nationals living overseas".
"I fought against (Socialist President Francois) Hollande for five years and can not back his heir", said 28-year-old parliamentary assistant Eric de La Fouchardiere, referring to Macron, a former adviser and minister of Hollande's, at an election night gathering on Sunday. Twenty-nine people were detained at the Bastille, where protesters waved red flags and sang "No Marine and No Macron!" in anger at the results.
Protesters burned cars, danced around bonfires and dodged riot police overnight at the Place de la Bastille and Republique.