"Everyone is very, very sad", Nadal said.
"I started the match very low and I played a very bad game in the second set when he break me", Nadal said.
German third seed and former world number one Kerber was bundled out after Ekaterina Makarova converted her eighth match point in Cincinnati. "To play Venus on such a big stage is a privilege for me and to play so well like I did, I'm really excited", Barty said.
Also doing double duty at the final major tuneup for the US Open was Spain s Rafael Nadal, assured of moving into the world number one ranking on Monday for the first time since July 2004.
No 7 Grigor Dimitrov is the top seed left in a men's field depleted by upsets and injuries - Roger Federer, Novak Djokovic, Andy Murray and defending champion Marin Cilic missed the tournament because of injuries.
The 31-year-old victor of 10 French Open crowns captured the ATP title this year at Barcelona as well as in Madrid, Monte Carlo and Roland Garros for his 15th Grand Slam crown in June. Croatia's Ivo Karlovic led Kyrgios 4-3 in their halted match.
Kyrgios will play the victor of the quarter-final between world No.1 Rafael Nadal and fellow Spaniard Albert Ramos Vinolas later on Friday.
Eighth-ranked Austrian Dominic Thiem, the only other seed remaining in Nadal's half of the draw, edged France's Adrian Mannarino 7-6 (7/4), 7-6 (7/3).
Kyrgios rips Nadal to reach Cincinnati semis
The 23rd-ranked Kyrgios will be playing in his first ATP Masters 1000 final - the highest-level final of his career.
Pliskova, last year's US Open runner-up, sought her fourth title of the year after Brisbane, Doha and Eastbourne.
"I was very surprised, you know, because you always hear what happened in Paris and in London, and you're, like, s--", Muguruza said. "If I deserve the place, for sure I will win it". But Halep has lost two prior matches this year with a chance to ascend to No. 1, falling to Jelena Ostapenko in the French Open final and to Konta in a Wimbledon quarterfinal after having won the first set in both matches.
Makarova advances to the third round, where she will play American Sloane Stephens, who beat 14th-seeded Petra Kvitova of the Czech Republic for the second straight week.
If Pliskova beats Wozniacki, she will force Halep to win the title to seize the top spot. It was a bad match for me.
"I just have, in my opinion, to be like today with the desire of winning with confidence and positive things".
Nadal was sloppy at the outset and on the defensive for much of a 6-2, 7-5 loss that lasted an hour and 20 minutes.
Muzaffarnagar train derailment: Four railway officials suspended
Unless safety is made an absolute priority at the human and technological levels, Indian Railways can't ensure passenger safety. In all these cases, Railways said that it suspected sabotage. "People are demanding basic facilities and a safe rail network".