Pal had complained of a progressive swelling of his scalp, headaches and a loss of vision in both eyes.
Pal is now recovering in the intensive care unit and is in stable condition, according to The Hindu.
Doctors are now waiting to see whether Pal will regain his eyesight.
"Such large tumors are rare and are a surgical challenge", lead surgeon Trimurti Nadkarni, the lead surgeon told news service SWNS.
When he was finally admitted to hospital with the enormous growth, his head had swelled so much that it looked like he had another head mounted on top of his. He said, "We had to cut open the scalp and remove the tumour".
Indian surgeons have removed what they say is the world's largest brain tumour.
"We have looked up medical literature from all over the world and it is the largest to be excised successfully".
Pal, a shopkeeper, had been living with the tumour for three years. The fact which makes this all the more astonishing is that the tumour weighs an unbelieveable 1.87 kilo grams which according to doctors might be the largest extracted tumour globally.
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Along with the tumour, even the affected skull bone was also removed during the surgery and they are awaiting the final medical reports to ascertain if it was benign or cancerous, he added.
Dr. Nadkarni said the tumour protruded from the skull and the scalp grew over it. "The part of the tumor within the skull was removed by making an opening in the skull".
Pal needed a transfusion of 11 units of blood and then spent three days on life support afterwards but has since made a good recovery.
He had been to three hospitals in Uttar Pradesh before the procedure in Mumbai but the doctors in those places had termed the tumor untreatable.
Santlal Pal, 31, was brought to Mumbai after several hospitals refused to admit him because they deemed the surgery too risky.
Pal and his relatives were informed about the high risk of surgery who prepared themselves for seven-hour long surgery which was successful.
The tumor has been sent for tests to detect malignancy (a term used for diseases in which abnormal cells divide without any control and can occupy tissues that are near them), The Hindu reported.