From one of tennis' established "Big Four" stars to one of the game's rising talents, but only the coming days will tell whether Alexander Zverev's marathon win Wednesday at the French Open could spark a grand slam breakthrough or be his downfall.
Dzumhur was battling Alexander Zverev in the fourth set of his round of 32 loss on Court Philippe-Chartrier in Paris. In the tiebreaker, Osaka went ahead 4-1, and held set points at 6-5 and 7-6.
While Zverev, whose brother Mischa is also playing in the third round, reached the last 16 at Wimbledon previous year, he has largely failed to live up to his world number three ranking in Grand Slams so far.
Even with his successes, he still is yet to defeat a Top 50 player in a Grand Slam, and has yet to make the quarterfinals of any of the four Major tournaments.
"I'm expecting another five-set match".
Frequently touted as a future world No.1, the 21-year-old's grand slam performance remains checkered, having never advanced past the fourth round in 11 tries.
Second seed Caroline Wozniacki eased into the fourth round with a crushing 6-0, 6-3 victory over local hope Pauline Parmentier.
The third-seeded pairing of Andreja Klepac and Maria Jose Martinez Sanchez beat the Americans 6-4, 6-7 (4), 6-0 to advance to the quarterfinals.
Pusha T's Latest Diss Track Put Drake's Soul In A Blackface Blender
Listen to Newsbeat live at 12:45 and 17:45 every weekday on BBC Radio 1 and 1Xtra - if you miss us you can listen back here. The line is a reference to the producer's battle with multiple sclerosis (MS), which he was diagnosed with back in 2005.
A exhausted Lajovic was unable to recover and that allowed Zverev to come to the fore, the world number three's quality finally shining through as he completed a gutsy victory with a service game to love. The German broke Dzumhur early on in the match to start the first set well, and broke for a second time to love a few games later at 4-2, eventually holding comfortably to win the first set after just 25 minutes of action.
In a meeting between the two youngest players remaining in the men's singles it was the 22-year-old Khachanov who secured a decisive second break to win the first set.
"None. Mainly I was thinking what I was going to have for lunch", said a deadpan Zverev after completing his 6-2 3-6 4-6 7-6 (3) 7-5 great escape.
Lajovic has enjoyed a fine renaissance in the clay-court season, reaching the quarter-finals in Madrid - beating Juan Martin del Potro along the way, while being narrowly beaten by Dominic Thiem in the semi-finals in Lyon a week prior to Roland Garros.
"I made the final of the U.S. Open but lost to my friend Sloane Stephens", the 23-year-old Keys said.
They were playing their match later Sunday on Court Suzanne Lenglen. Svitolina, who had twice played quarter-finals in the French Open, was defeated by Romanian Mihaela Buzarnescu 6-3 and 7-5 in a 2-0 set. Serving the ninth game, Dzumhur saved a break point and immediately held advantage point to win 5-4. He was two points from the match but Dimitrov won back to back points to extend the match.